Here's a cool John Mayer lick in "The Last Train Home." It happens during the fade-out at 2:48. It's basically a simple B.B. King-style lick that he plays at different spots across the neck, covering 3 octaves. This kind of repetition creates an interesting sound despite the fact that you're just playing the same notes in different places.

You can use this technique with any lick you know. Just map out how to play the lick on different strings and practice flowing between them.

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